Patient Tony Orlando needs his wisdom teeth pulled, but nurse Lena Kelly has other things in store for him. After putting him under and giving him a "botched circumcision," she convinces him that the only way he'll be able to lead a normal life is to undergo a feminization procedure and to live out the rest of his days as a cute little trans girl. Convinced by her sound logic, she gives him a potent estrogen suppository and he slips off into a short coma. As nurse Lena wakes him a few days later, he finds that he's no longer a he, but a she! The nurse tells her that her new name is Natalie and that she's going to have to become a huge anal slut to really get the most out of her new body, then proceeds to give her an extremely thorough rectal exam...